Die Übersicht der Publikationen 1998 als PDF

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Originalarbeiten

Baer FM, Theissen P, Schneider CA, Voth E, Sechtem U,
Schneider CA, Schicha H, Erdmann E
Dobutamine magnetic resonance imaging predicts contractile
recovery of chronically dysfunctional myocardium after successful
revascularization.
J Am Coll Cardiol, 1998; 31: 1040-1048

Bäumer AT, Flesch M, Kilter H, Philipson KD, Böhm M
Overexpression of the Na+-Ca2+ exchanger leads to enhanced
inotropic responsiveness to Na +-channel agonist without
sarcoplasmic reticulum protein changes in transgenic mice.
Biochem Biophys Res Comm, 1998; 249: 786-790

Bavendiek U, Brixius K, Pietsch M, Groß A, Zobel C, Müller-Ehmsen
J, Schwinger RHG
Effect of inotropic interventions on the force-frequency relation in the
human Heart.
Basic Res Cardiol, 1998; 93: 76-85

Böhm M, Castellano M, Flesch M, Maack Ch, Moll M, Paul M,
Schiffer F, Zolk O
Chamber-specific alterations of norepinephrine uptake sites in
cardiac hypertrophy.
Hypertension, 1998; 32: 831-837

Böhm M, Ettelbrück S, Flesch M, van Gilst WH, Knorr A, Maack C,
Pinto YM, Paul M, Teismann CH, Zolk O
ß-Adrenergic signal transduction following carvedilol treatment in
hypertensive cardiac hypertrophy.
Cardiovasc Res, 1998; 40: 146-155

Böhm M, Zolk O, Flesch M, Schiffer F, Schnabel P, Stasch JP, Knorr
A
Effects of AT1 receptor blockade and ACE inhibition on cardiac
ß-adrenergic signal transduction.
Hypertension, 1998; 31: 747-754

Bohnemeier H, Pinto Y, Horkay F, Toth M, Juhász-Nagy A,
Orzechowski HD, Böhm M, Paul M
Endothelin converting-enzyme-1 mRNA expression in human
cardiovascular disease.
Clin Exp Hypert, 1998; 20: 417-437

Brixius K, Frank K, Münch G, Müller-Ehmsen J, Schwinger RHG
WS 1442 (Crataegus-Spezialextrakt) wirkt am insuffizienten
menschlichen Myokard Kontraktionskraft-steigernd.
Herz/Kreislauf, 1998; 30: 28-33

Brixius K, Mohr V, Müller-Ehmsen J, Hoischen S, Münch G,
Schwinger RHG
Potent vasodilatory with minor cardiodepressant actions of
mibefradil in human cardiac tissue.
Br J Pharmacol, 1998; 125: 41-48

Burkhard-Meier C., Deutsch HJ, Hartmann I, Höpp HW, Erdmann E
Behandlung von Aortenisthmusstenosen bei Erwachsenen mittels
Ballondilatation und Stenting.
Dtsch med Wschr, 1998; 123: 361

Deutsch HJ, Burkhard-Meier C, LaRosée K, H.W. Höpp
Katheter-interventioneller Verschluß interatrialer
Kurzschlußverbindungen beim Erwachsenen.
Dtsch med Wschr, 1998; 123: 366

Endres M, Laufs U, Huang Z, Nakamura T, Huang P, Moskowitz MA,
Liao JK
Stroke protection by 3-hydroxy-3-methylglutaryl /HMG)-CoA
reductase inhibitors mediated by endothelial nitric oxide synthase.
Proc Natl Acad Sci, 1998; 15: 8880-8885

Erbel R, Haude M, Höpp HW, Franzen D, Rupprecht HJ, Heublein D,
Fischer K, deJaegere P, Serruys P, Rutsch W, Probst for the REST-
Study Group:
Coronary-artery stenting compared with balloon angioplasty for
restenosis after initial balloon angioplasty.
N Engl J Med, 1998; Med 339:1672

Flesch M, Schwarz A, Böhm M
Effects of red and white wine on endothelial-dependent
vasorelaxation of rat aorta and human coronary arteries.
Am J Physiol, 1998; 275: H1183-1190

Frank K, Bölck B, Bavendiek U, Schwinger RHG
Frequency dependent force generation correlates with sarcoplasmic
calcium ATPase activity in human myocardium.
Basic Res Cardiol, 1998; 93: 405-411

Franzen D, Sechtem U, Höpp HW
Comparison of angioscopic, intravascular ultrasonic, and
angiographic detection of thrombus in coronary stenosis.
Am J Cardiol, 1998; 82: 1273

Hoischen S, Brixius K, Schwinger RHG
T-and L-type Ca2+-channel antagonists reduce contractility in guinea
pig cardiac myocytes.
J Cardiovasc Pharmacol, 1998; 32: 323-330

Hoppe UC, Beuckelmann DJ
Characterization of the hyperpolarization-activated inward current in
isolated human atrial myocytes.
Cardiovasc Res, 1998; 38: 788-801

Hoppe UC, Beuckelmann DJ
Modulation of the hyperpolarization-activated inward current (If) by
antiarrhythmic agents in isolated human atrial myocytes.
Naunyn Schmiedebergs Arch Pharmacol, 1998; 358: 635-4o

Hoppe UC, Jansen E, Südkamp M, Beuckelmann DJ
A hyperpolarization-activated inward current (If ) in ventricular
myocytes from normal and failing human hearts.
Circulation, 1998; 97: 55-65

Kääb S, Dixon J, Duc J, Ashen D, Näbauer M, Beuckelmann DJ,
Steinbeck G, McKinnon D, Tomaselli GF

Molecular basis of transient outward potassium current
downregulation in human heart failure. A decrease in Kv4.3 mRNA
correlates with a reduction in current density.
Circulation, 1998; 98: 1383-1393

Laufs U, Endres M, Moskowitz MA, Liao JK
Regulation of endothelial nitric oxide production by inhibition of
HMG-CoA reductase.
http://www.mcmaster.ca/inabis98/index.html

Laufs U, La Fata V, Plutzky J, Liao JK
Upregulation of endothelial nitric oxide synthase by HMG-CoA
reductase inhibitors.
Circulation, 1998; 97: 1129-1135

Laufs U, Liao JK
Post-transcriptional regulation of endothelial nitric oxide synthase
mRNA stability by Rho GTPase.
J Biol Chem, 1998; 273: 24266-24271

Lindner M, Erdmann E, Beuckelmann DJ
Calcium content of the sarcoplasmic reticulum in isolated ventricular
myocytes from patients with terminal heart failure.
J Mol Cell Cardiol, 1998; 30: 743-749

Marwick T, Brunken R, Meland N, Brochet E, Baer FM, Binder T,
Flachskampf F, Kamp O, Nienhaber C, Nihoyannopoulos P, Pierard
L, Vanoverschelde JL, Wouw P, Lindvall K
Accuracy and feasibility of contrast echocardiography for detection
of perfusion defects in routine practice: comparison with wall motion
and MIBI-SPECT.
J Am Coll Cardiol, 1998; 32: 1260-1269

Mittmann C, Münstermann U, Weil J, Böhm M, Herzig S, Nienaber
C,Eschenhagen T
Analysis of gene expression patterns in small amounts of human
ventricular myocardium by a multiplex Rnase protection assay.
J Mol Med, 1998; 76: 133-140

Müller-Ehmsen J, Brixius K, Schwinger RHG
Positive inotropic effects of the novel Na+-channel modulator BDF
9198 in human nonfailing and failing myocardium.
J Cardiovasc Pharmacol, 1998; 31: 684-689

Münch G, Bölck B, Hoischen S, Brixius K, Bloch W, Reuter H,
Schwinger RHG
Unchanged protein expression of sarcoplasmic reticulum
Ca2+-ATPase, phospholamban and calsequestrin in terminally
failing human myocardium.
J Mol Med, 1998; 76:434-441

Nickenig G, Bäumer AT, Grohe C, Kahlert S, Strehlow K,
Rosenkranz S, Stäblein A, Beckers F, Smits JFM, Daemen JAP,
Vetter H, Böhm M
Estrogen modulates AT1 receptor gene expression in vitro and in
vivo.
Circulation, 1998; 97: 2197-2201

Nickenig G, Röling J, Strehlow K, Schnabel P, Böhm M
Insulin induces up-regulation of vascular AT1 receptor gene
expression by posttranscriptional mechanisms.
Circulation, 1998; 98: 2453-2460

Nickenig G, Strehlow K, Roeling J, Zolk O, Böhm M
Salt induces vascular AT1 receptor overexpression in vitro and in
vivo.
Hypertension, 1998; 31: 1272-1277

Pönicke K, Vogelsang M, Heinroth M, Becker K, Zolk O, Böhm M,
Zerkowski HR, Brodde OE
Endothelin-receptors in the failing and non-failing human heart.
Circulation, 1998; 97: 744-751

Priebe L, Beuckelmann DJ
Simulation study of cellular electric properties in heart failure.
Circ Res, 1998; 82: 12o6-1223

Priebe L, Beuckelmann DJ
Cell swelling causes the action potential duration to shorten in
guinea-pig ventricular myocytes by activating/KAT.
Pflügers Arch - Eur J Physiol, 1998; 436: 894-898

Sievert H, Babic UU, Hausdorf G, Schneider M, Höpp HW, Pfeiffer
D, Pfisterer M, Friedli B, Urban P
for the ASDOS Study Group:
Transcatheter closure of atrial septal defect and patent foramen
ovale with the ASDOS Device (A Multi Institutional European Trial)
Am J Cardiol, 1998; 82: 1405

Sitzler G, Zolk O, Laufs U, Paul M, Böhm M
The vascular ß-adrenergic receptor adenylyl cyclase system from
renin-transgenic hypertensive rats.
Hypertension, 1998; 31: 1157-1165

Schnabel P, Camps M
Activation of a phospholipase C-ß2 deletion mutant by limited
proteolysis.
Biochem J, 1998; 330: 461-468

Schneider CA, Helmig AK, Baer FM, Horst M, Erdmann E, Sechtem
U
Significance of exercise induced ST-segment elevation and T-wave
pseudonormalization for improvement of function in healed Q-wave
myocardial infarction.
Am J Cardiol, 1998; 82: 148-153

Schneider CA, Voth E, Gawlich S, Baer FM, Horst M, Schicha H,
Erdmann E, Sechtem U
Significance of rest technetium-99 m sestamibi imaging for the
prediction of improvement of left ventricular dysfunction after Q-wave
myocardial infarction: importance of infarct location adjusted
thresholds.
J Am Coll Cardiol, 1998; 32: 648-654

Schröder F, Handrock R, Beuckelmann DJ, Hirt S, Hullin R, Priebe
L, Schwinger RHG, Weil J, Herzig S
Increased availability and open probability of single L-type calcium
channels from failing compared with nonfailing human ventricle.
Circulation, 1998; 98: 969-976

Teismann AC, Pinto YM, Buikema H, Flesch M, Böhm M, Paul M,
van Gilst WH
Dissociation of blood pressure reduction from end-organ damage in
TGR (mREN2)27 transgenic hypertensive rats.
J Hyperten, 1998; 16: 1759-1765

Thompson DR, Shepherd J, Alcade V, Befort PA, Boucher B,
Erdmann E, Gutzwiller F, van Hemert T, Jordan-Ghizzo I, Menotti A,
Schioldborg P, Turner M, Umlauf B
Awareness of and attitude to coronary heart disease among the
public, patients and family members: the HELP study.
Coronary Health Care, 1998; 2: 33-38

Weltermann BM., Korbonitz G, Küching A, Martin S, Adl S, Höpp
HW
Wiederholungsuntersuchungen an der Schnittstelle von ambulanter
zu stationärer Versorgung.
Gesundh Ökon Qual Manag 1998; 3: 88

Zobel C, Brixius K, Pietsch M, Münch G, Bölck B, Schwinger RHG
Unchanged SR-Ca 2+-ATPase activity, reduced Ca2+-sensitivity and
a negative force-frequency-relationship in (TG(mREN-2)27) rats
overexpressing the mouse renin gene.
J Mol Med, 1998; 76: 533-544

Zobel C, Brixius K, Schwinger RHG
Effect of the Na+-channel modulator BDF 9148 and Ca2+-sensitivity
and force of contraction of hypertrophic myocardium from transgene
rats harboring the mouse renin gene (TG(mREN2)27).
Naunyn Schmiedeberg's Arch Pharmacol, 1998; 357:532-539

Zolk O, Flesch M, Schnabel P, Teisman AC, Pinto Y, van Gilst WH,
Paul M, Böhm M
Differential effects of quinapril, losartan, and hydralazine on cardiac
ß-adrenergic neuroeffector mechanisms in hypertensive cardiac
hypertrophy.
Brit J Pharmacol, 1998; 123: 405-412

Zolk O, Kilter H, Flesch M, Mansier P, Swynghedauw B, Schnabel P,
Böhm M
Functional coupling of overexpressed ß1-adrenoceptors in the
myocardium of transgenic mice.
Biochem Biophys Res Comm, 1998; 248: 801-805

Bücher und Herausgeberschaften

Beuckelmann D, Böhm M
Betablockertherapie der Herzinsuffizienz
UNI-MED Verlag AG Bremen; 1998

Böhm M, Laragh JH, Zehender M
From Hypertension to Heart Failure; 1998
Springer Verlag, Heidelberg, New York

Böhm M, Schnabel P
Transition from cardiac hypertrophy to failure
Journal of Molecular Medicine (Focussed Issue); 1998
Springer Verlag, Heidelberg, New York

Cleland JGF, Erdmann E
Health economics and quality of life issues in heart failure.
European Heart Journal; 1998, 19 (Suppl P), P1

Endres M, Laufs U, Liao JK, Moskowitz MA
Specific upregulation of endothelial nitric oxide synthase and its
potential importance to cerebral ischemia.
In: Pharmacology of Cerebral Ischemia, ed. J. Krieglstein,
Medpharm Scientific Publishers Stuttgart, 1998

Erdmann E (Herausg.)
Herz/Kreislauf, Richard Pflaume Verlag, 1998

Erdmann E (Schriftleiter)
Deutsch Med Wschr, Thieme Verlag, 1998

Übersichtsarbeiten, Kongreßbeiträge, Buchartikel

Baer FM
Vitalitätsdiagnostik bei koronarer Herzerkrankung.
Med Welt, 1998; 49: 354-358

Baer FM
Die endotheliale Dysfunktion - hat sie eine praktische Bedeutung?
Herz/Kreislauf, 1998; 30: 284-287

Baer FM, Deutsch HJ
Transösophageale Streßechokardiographie.
In.: Streßechokardiographie. Haug ed., 1998; PP 359-366,
Steinkopff Darmstadt

Baer FM, Erdmann E
Methods of assessment and clinical relevance of myocardial
hibernation and stunning.
Thorac Cardiovasc Surg, 1998; 46: 264-269

Baer FM, Erdmann E
Elektronenstrahl-Computertomographie (EBCT) - ein Meilenstein in
der Diagnostik der koronaren Herzkrankheit?
Dtsch med Wschr, 1998; 123: 1399-1401

Baer FM, Theissen P, Crnac J, Schmidt M
Assessment of myocardial viability with MR - the Cologne
perspective.
Magnetic Resonance Materials in Physics, Biology and Medicine,
1998; 6: 140-142

Beuckelmann DJ
Ist die koronare Herzkrankheit eine Infektionskrankheit?
Herz/Kreisl, 1998; 3o: 425-428

Beuckelmann DJ
Infektionsgenese der koronaren Herzkrankheit - klinisch relevant?
Präv-Rehab, 1998; 1o: 45-46

Böhm M
Wann Thrombolyse?
Internist, 1998; 39: 216-217

Böhm M
Vorgehen bei intrakardialen Thromben.
Internist, 1998; 39: 218-219

Böhm M
Catecholamine refractoriness and their mechanisms in
cardiocirculatory shock and chronic heart failure.
Thorac Cardiovasc Surg, 1998; 46: 270-276

Böhm M
Echokardiographie: Gibt es einen Nutzen in der präoperativen
Risikoabschätzung bei nichtkardialen operativen Eingriffen?
Anaesthesist, 1998 47: 901-902

Böhm M
Präoperative Diagnostik der koronaren Herzkrankheit: Was ist nötig,
was ist sinnvoll?
Anästhesiol Intensivmed Notfallmed Schmerther, 1998; 33: 11-15

Böhm M, Paul M
Kardiovaskuläre Erkrankungen
in Klinikleitfaden: Arzneitherapie.
Gustav Fischer Verlag, Lübeck, Stuttgart, Jena, Ulm, 1998; pp
196-285

Burkhard-Meier C, Deutsch HJ, Hartmann I, Höpp HW, Erdmann E
Die Behandlung der Aortenisthmusstenose beim Erwachsenen mit
Ballondilatation und Stent-Implantation.
Dtsch med Wschr, 1998; 123: 361-365

Cremers B, Böhm M
Therapierelevante pathophysiologische Aspekte der chronischen
Herzinsuffizienz.
Kassenarzt, 1998; 49: 44-52

De Catarina R, Laufs U
Prevenzione e terapia del danno vascolare e della disfunzione
endoteliale con agenti ipocolesterolemizzanti.
In: Proceedings of the 31° Convegno Internazionale di Cardiologia
1997.
Scientific Press, Florence:: 563-585

Deutsch HJ, Voth E, Baer FM
Streßechokardiographie im Vergleich zur
Positronenemissionstomographie.
In: Streßechokardiographie. Haug ed., 1998; pp 228-233, Steinkopff
Darmstadt

Dieck D., Hoeth U, Schrappe H, Höpp HW
Planung und Umsetzung von Informationssystemen zur
Qualitätssicherung in der Kardiologie.
Quali Med, 1998; 6: 5

Endres M, Laufs U
HMG-CoA Reduktasehemmer und Schlaganfallrisiko.
Nervenarzt, 1998; 69: 717-721

Erdmann E
Pathophysiology of heart failure.
Heart, 1998; 79: 3-5

Erdmann E
Chronic cardiac insufficiency: therapy with beta-adrenergic blockers.
J Clin Bas Cardiol, 1998; 1: 10-13

Erdmann E
Digitalis - von der Rezeptorforschung zur Differentialtherapie.
Essener Kardiologische Kardiovaskuläre Nachrichten, 1998; 1-18

Erdmann E
Die Therapie der chronischen Herzinsuffizienz mit
ß-Rezeptorenblockern.
Z Kardiol, 1998; 5: 458-464

Erdmann E
Digitalis therapy - Relevance of heart rate reduction.
Basic Res Cardiol, 1998; 93: 156-159

Erdmann E
Präoperative Untersuchung und Risikoeinschätzung.
Klinik der Gegenwart, 1998; 6: 1-16

Erdmann E, Diet F
Anti-Cardiolipin-Antikörper-Titer bei Herzinfarkt.
Dtsch med Wschr, 1998; 123: 748-749

Flesch M, Erdmann E
Ätiologische Diagnostik und Therapie der Perikarditis und des
Perikardergusses.
Internist, 1998; 39: 1297-1300

Flesch M, Erdmann E, Böhm M
Alkohol und Myokardinfarkt. Epidemiologische und experimentelle
Untersuchungen zum Einfluß von Alkohol auf Gefäßrelaxation und
Koronarsklerose.
Dtsch med Wschr. 1998; 123: 1490-1496

Flesch M, Maack C, Böhm M
Hypertonie - Hypertrophie - Herzinsuffizienz. Ein gradueller
Übergang?
Herz/Kreisl, 1998; (Suppl V) 30: 12-18

Hajjar RJ, Müller FU, Schmitz W, Schnabel P, Böhm M
Molecular aspects of adrenergic signal transduction in cardiac
failure.
J Mol Med, 1998; 76: 747-755

Hoppe U, Erdmann E
Supraventrikuläre Tachykardien - Ist die konservative Therapie
heutzutage noch gerechtfertigt?
Herz/Kreislauf, 1998; 30: 237-240

Hoppe U, Erdmann E
Leitlinien zur Therapie der chronischen Herzinsuffizienz.
Z Kardiol, 1998; 87: 645-661

Hoppe U, Erdmann E
Aortenisthmusstenose - Langzeitprognose auch nach effektiver
Korrektur eingeschränkt.
Herz/Kreislauf, 1998; 30: 115-122

Horst M, Eichstaedt HC, Baer FM, Voth E, Zirbes T, deVivie ER
Diagnostic procedures fail to verify laser channel patency despite
clinical improvement in patients following isolated and combined
TMLR.
In: Transmyocardial laser revascularization. Scientific basis and
clinical value. Krabatsch T, Hetzer R eds., 1998; pp 60-66, Ecomed

Kilter H, Jansen W, Höpp HW
Das koronare Subclavian Steal-Syndrom.
Herz/Kreisl, 1998; 30: 375

Laufs E, Erdmann E
Stickstoffmonoxid als Signalmolekül im Herz-Kreislaufsystem.
Dtsch med Wschr, 1998; 123: 1562-1565

Maack C, Böhm M
ß-Blocker treatment of chronic heart failure.
in: From Hypertension to Heart Failure, Hrsg. Böhm M, Laragh JH,
Zehender M, Springer-Verlag, 1998; 177-205

Meyer J, Breithardt G, Erbel R, Erdmann E, Gohlke H, Hanrath P,
Sonntag F, Steinbeck G
Leitlinie: Koronare Herzkrankheit/Angina pectoris.
Z Kardiol, 1998; 87: 907-911

Movsesian MA, Schwinger RHG
Calcium sequestration by the sarcoplasmic reticulum in heart failure.
Cardiovasc Res, 1998; 37: 352-359

Müller-Ehmsen J, Schwinger RHG
Enhanced sensitivity of the failing human myocardium towards
agents which increase intracellular Na+-concentration.
Herz/Kreislauf, 1998; 30: 170-175

Nickenig G, Bäumer AT, Böhm M
Die pathophysiologische Bedeutung der AT1-Rezeptorregulation
während der Östrogendefizienz.
Herz/Kreisl, 1998; 30 (Suppl V): 24-27

Nickenig G, Böhm M
Cardiac specific expression of AT1 receptors in experimental heart
failure.
Heart Failure Reviews, 1998; 3: 101-107

Nickenig G, Böhm M
Herzinsuffizienz und Hochdrucktherapie.
Pressure, 1998; 2: 2-6

Nickenig G, Böhm M
Interaction between insulin and AT1 receptor. Relevance for
hypertension and arteriosclerosis.
Basic Res Cardiol, 1998; 93: (Suppl. 2) 135-139

Nickenig G, Böhm M
Vaskuläre AT1-Rezeptoren bei arterieller Hypertonie und
metablischem Syndrom.
Herz/Kreisl, 1998; 30: 329-334

Nickenig G, Böhm M
AT1-Rezeptor-Antagonisten -
Gemeinsamkeiten und Unterschiede
Herz/Kreisl, 1998; 30 (Suppl V): 19-23

Nickenig G, Böhm M
Die Therapie des Myokardinfarktes mit ACE-Hemmern.
Herz/Kreisl, 1998; 30: 378-381

Nickenig G, Böhm M
'Überexpression des AT1 Rezeptors für KHK bedeutsam.
Fortschritt Med, 1998; 5: 44-45

Nickenig G, Böhm M, Erdmann E
Chronische Herzinsuffizienz. Modern therapieren!
Aktuelles Praxiswissen. Herz/Kreisl, 1998; 2: 6-10

Nickenig G, Waßmann S, Böhm M
Beeinflussung der Nitrattoleranz durch Antioxidantien.
Dtsch med Wschr, 1998; 123: 1556-1561

Sechtem U, Baer FM, Theissen P, Voth E, Schicha H
Assessment of myocardial viability by magnetic resonance
techniques.
In: Current and future applications of magnetic resonance in
cardiovascular disease. Higgins CB, Ingwall JS, Pohost GM eds.:
pp 267-282, Futura Publishing Company NY, 1998

Schnabel P, Böhm M
Summary of the Cologne Conference on Heart Failure:
Transition from cardiac hypertrophy to failure.
J Mol Med, 1998; 76: 721-722

Schnabel P, Flesch M, Böhm M
ß-adrenergic signal transduction defects in heart failure.
in: From Hypertension to Heart Failure, Hrsg. Böhm M, Laragh JH,
Zehender M, Springer-Verlag, 1998; 159-176

Schwinger RHG, Bölck B, Münch G, Brixius K, Müller-Ehmsen J,
Erdmann E
cAMP-dependent protein kinase A stimulated sarcoplasmic
reticulum function in heart failure.
Ann New York Acad Sci, 1998; 853: 240-250

Stula M, Pinto YM, Gschwend S, Teismann AC, van Gilst WH, Böhm
M, Dietz R, Paul M
Interaction of the renin-angiotensin system and the endothelin
system in cardiac hypertrophy.
J Cardiovasc Pharmacol, 1998; 31 (Suppl 1): 403-405

Zolk O. Flesch M, Nickenig G, Schnabel P, Böhm M
Alteration of intracellular Ca2+-handling and receptor regulation in
hypertensive cardiac hypertrophy: insights from Ren2-transgenic
rats.
Cardiovasc Res, 1998; 39: 242-256

Kasuistiken

Böhm M
Holt-Oram Syndrome.
Circulation, 1998; 98: 2636-2637

Burkhard-Meier C, Deutsch HJ, LaRoseè K, Höpp HW, Erdmann E
Katheterinterventioneller Verschluß eines offenen Foramen ovale
mittels ASDOS-Schirm-System bei einer 43jährigen Patientin nach
Hirninfarkt.
Herz/Kreislauf, 1998; 30: 84-88

Hoppe UC, Beuckelmann DJ, Böhm M, Erdmann E
A young mother with severe chest pain.
Heart, 1998; 79: 205

Laufs U, Schneider C, Wassermann K, Erdmann E
Chronic eosinophilic pneumonia with atypical radiographic
presentation.
Respiration, 1998; 65: 323-326

Maack Ch, Stäblein A, Böhm M
Antitumour treatment leading to heart failure in a hypertensive
patient.
Experta Medica Communication, 1998; 33-45

Rosenkranz S, Stäblein A, Deutsch HJ, Verhoeven HW, Erdmann E
Anomalous drainage of the right superior vena cava into the left
atrium in a 61-year-old woman.
Int J Cardiol, 1998; 64: 285-291

Würker M, Szelies B, Heindel W, Böhm M, Fischbach R, Heiß WD
Mykotisches Aneurysma bei Endocarditis lenta als Ursache für
intraparenchymatöse Hirnblutung.
Med Klin, 1998; 93: 307-310

Vorträge und Poster

Baer FM, Voth E, LaRoseè K, Theissen P, Crnac J, Schmidt M,
Schneider CA, Deutsch HJ, Schicha H, Erdmann E
Predictive value of functional and metabolic parameters of
myocardial viability for the post-revascularization recovery of left
ventricular function: dobutamine-TEE and dobutamine-MRI versus
FDG-PET.
Eur Heart J, 1998; (Supll) 19: 629

Baer FM, Voth E, Schneider CA, Theissen P, Crnac J, Schmidt M,
Horst M, Kettering K, Sechtem U, Erdmann E
Dobutamine magnetic resonance imaging is a reliable alternative to
positron emission tomography for the prediction of functional
recovery of viable myocardium after successful revascularization.
Circulation, 1998; (Suppl): I 513

Baer FM, Voth E, Schneider CA, Theissen P, Crnac J, Schmidt M,
Horst M, Kettering K, Sechtem U
Dobutamine magnetic resonance imaging versus
18-F-Fluorodeoxyglucose positron emission tomography: predictive
value for the functional recovery of viable myocardium after
successful revascularization.
Eur Heart J, 1998; (Supll) 19: 30

Bäumer AT, Flesch M, Kilter H, Philipson KD, Böhm M
Einfluß einer Überexpression des kardialen Na/Ca Austauschers auf
die Modulation der kardialen Kontraktionskraft und die Proteine des
sarkoplasmatischen Retikulums
Z Kardiol, 1998; 87 (Suppl 1): 146

Bäumer AT, Flesch M, Kilter H, Philipson KD, Böhm M
Inotropic responsiveness to Na+-channel agonists and sarcoplasmic
reticulum proteins in hearts of transgenic mice overexpressing the
Na+-Ca2+-exchanger.
Naunyn-Schmiedeberg's Arch Pharmacol, 1998; 357 (Suppl 4): R
110

Bäumer AT, Flesch M, Kilter H, Philipson KD, Böhm M
Inotropic responsiveness to Na+-channel agoonists and
sarcoplasmic reticulum proteins in hearts of transgenic mice
overexpressing the Na+- Ca2+-exchanger.
Eur Heart J, 1998; 19: 3403

Bäumer AT, Grohe C, Kahlert S, Beckers F, Stäblein A, Nickenig G,
Böhm M
Östrogen moduliert den vaskulären AT1 Rezeptor in vitro und in vivo.
Z Kardiol, 1998; 87 (Suppl 1): 270

Bäumer AT, Nickenig G, Böhm M
Evidence for a novel human angiotensin receptor sutype.
Eur Heart J, 1998; 19: 1507

Bäumer AT, Nickenig G, Grohe C, Kahlert S, Strehlow K, Stäblein A,
Smits JFM, Daemen MJAP, Vetter H, Böhm M
Oestrogen modulates AT1 receptor gene expression in vitro and in
vivo.
Eur Heart J, 1998; 19: P2129

Baudler S, Nickenig G, Böhm M
Untersuchung der Genexpression der dilatativen Kardiomyopathie.
Z Kardiol, 1998; 87 (Suppl 1): 186

Böhm M
Hormontherapie bei Herzinsuffizienz.
Z Kardiol, 1998; 87 (Suppl 1): 62

Böhm M
Therapierelevante pathophysiologische Aspekte der chronischen
Herzinsuffizienz.
Med Klin, 1998; 93 Suppl I: 69

Böhm M
Kardiogener Schock: Positiv inotrope Substanzen.
Z Kardiol, 1998; 87: 2295

Böhm M, Nickenig G
AT1 receptor regulation by insulin, sodium and lipids.
Pharm Pharmacol Lett 8, 1998; 2: 6

Bölck B, Münch G, Brixius K, Sugaro A, Schwinger RHG
Verminderter Phosphorylierungsgrad von
Threonin-17-Phospholamban an insuffizientem menschlichem
Myokard.
Z Kardiol, 1998; 87 (Suppl 1) 306

Bölck B, Münch G, Hoischen S, Brixius K, Schwinger RHG
Reduced Ca2+-sensitivity and activity of SERCA 2 in failing human
myocardium due to reduced serine-16 and threonine-17
phospholamban phosphorylation.
Circulation, 1998; (Suppl) 98: 1897

Brixius K, Reicke S, Reuter H, Schwinger RHG
Effect of the Ca2+-sensitizers EMD 57033 and CGP 48506 on the
myosin ATPase/force-ratio in human failing and nonfailing
myocardium.
Circulation, 1998; (Suppl) 98: 3049

Ettelbrück S, Flesch M, Rosenkranz S, Maack C, Böhm M
Carvedilol and metoprolol improve coupling of ß-adrenoceptors in
isoprenaline-treated cardiomyocytes.
Naunyn-Schmiedeberg's Arch Pharmacol, 1998; 357 (Suppl 4): R
104

Ettelbrück S, Flesch M, Rosenkranz S, Maack C, Böhm M
Verbesserte Kopplung von ß-Adrenozeptoren in
isoprenalinbehandelten Kardiomyozyten durch Carvedilol und
Metoprolol.
Z Kardiol, 1998; 87 (Suppl 1): 123

Flesch M, Böhm M
Effects of red and white wine on endothelial-dependent
vasorelaxation of rat aorta and human coronary arteries.
Kidney Blood Press Res, 1998; 21 (Suppl): 346

Flesch M, Ettelbrück S, Rosenkranz S, Maack C, Bäumer AT, Böhm
M
Functional activation of spare receptors in rat ventricular cardiac
myocytes by carvedilol.
Eur Heart J, 1998; 19: 1978

Flesch M, Kilter H, Cremers B, Laufs U, Mädge M, Böhm M
Bedeutung der Freisetzung von Stickstoffmonoxid und freier
Radikale für die kardiale Dysfunktion im septischen Schock.
Med Klin, 1998; 93 Suppl I: 113

Flesch M, Maack C, Kuhn-Regnier F, Böhm M
Effect of hydroxl radicals on force on contraction, diastolic tension,
force-frequency-relationship and sarcoplasmic reticulum Ca2+
-ATPase activity in human myocardium.
Naunyn-Schmiedeberg's Arch Pharmacol, 1998; 357 (Suppl 4): R
102

Flesch M, Maack C, Südkamp M, Böhm M
Effect of ß-blockers on free radical-induced cardiac contractile
dysfunction.
Kidney Blood Press Res, 1998; 21 (Suppl): 346

Frank K, Reicke S, Brixius K, Schwinger RHG
Levosimendan wirkt am insuffizienten menschlichen Myokard nicht
Kontraktionskraft-steigernd.
Z Kardiol, 1998; 87 (Suppl 1) 399

Hoppe UC, Jansen E, Beuckelmann DJ
Modulation des hyperpolarisations-aktivierbaren Einwärtsstromes I f
durch Adenosin, Carbachol und Isoproterenol.
Z Kardiol, 1998; (Suppl. I) 87: 125

Kettering D, Dapunt O, Eichstedt HC, Baer FM
Early results after minimally invasive coronary bypass grafting.
Eur Heart J, 1998; (Suppl) 19: 263

Köster OF, Beuckelmann DJ
A Ca²+i-dependent current in human myocardium in the absence of
Na+/Ca²+-exchange current.
Eur Heart J, 1998; 19: 111

Koester O, Beuckellmann DJ
Ca2+ release and its electrical effects in human atrial und ventricular
cardiomyocytes.
Circulation, 1998; (Suppl) 98: I-188

La Fata V, Laufs U, Liao JK
Functional analysis of the endothelial nitric oxide synthase promoter
in response to laminar flow.
J Invest Med, 1998; 46(3): 190A

La Fata V, Laufs U, Spiecker M, Peng H-B, Liu F, Sessa WC, Shyy
J, Liao JK
Requirement of GATA binding proteins for induction of endothelial
nitric oxide synthase transcription by laminar flow. Circulation, 1998;
98(17): I-312

Laufs U, Endres M, Huang PL, Moskowitz MA, Liao JK
HMG-CoA reductase inhibitors reduce cerebral infarct size by
upregulating endothelial nitric oxide synthase.
JACC 31, 1998; (2, Suppl. A): 406-4

Laufs U, Endres M, Huang PL, Moskowitz MA, Liao JK
HMG-CoA Reduktasehemmer reduzieren Schlaganfallgröße durch
Hochregulation der endothelialen NO Synthase.
Z Kardiol, 1998; 87 (Suppl 1): 6

Laufs U, La Fata V, Liao JK
Hochregulation der endothelialen Stickstoffmonoxidsynthase durch
Hemmung der HMG CoA Reduktase.
Z Kardiol, 1998; 87 (Suppl 1): 30

Laufs U, La Fata V, Liao JK
Hemmung der Mevalonatsynthese verhindert die Herabregulation
der endothelialen Stickstoffmonoxidsynthase durch
Sauerstoffmangel.
Z Kardiol, 1998; 87 (Suppl 1): 239

Laufs U, Liao JK
HMG-CoA reductase inhibitors prevent inhibition of Gi-proteins by
oxidized low-density lipoprotein.
Circulation, 1998; 98(17): I-235

Laufs U, Liao JK
Regulation of endothelial nitric oxide synthase expression by Rho
GTPase. Circulation, 1998; 98(17): I-313

Laufs U, Liao JK
Cytoskeletal regulation of endothelial nitric oxide synthase.
Circulation, 1998; 98(17): I-405

Laufs U, Miyamoto A, Liao JK
Die Ligandenbindungsaffinität und G-Protein vermittelte
Signaltransduktion des Bradykinin Rezeptors werden durch
Stickstoffmonoxid reguliert.
Z Kardiol, 1998; 87 (Suppl 1): 71

Lindner M, Beuckelmann DJ
Calcium-sparks in human ventricular myocytes.
Eur Heart J, 1998; 19: 6o9

Lindner M, Sauer H. Hescheler J, Beuckelmann DJ
Calcium-sparks in human failing myocardium.
Circulation, 1998; (Suppl) 98: I-764

Lindner M, Sauer H, Hescheler J, Beuckelmann DJ
Calcium-Sparks in humanen ventrikulären Herzmuskelzellen.
Z Kardiol, 1998; (Suppl. I) 87: 51

Maack C, Flesch M, Südkamp M, Böhm M
Einfluß von Hydroxylradikalen auf die kardiale Kontraktionskraft, die
Kraft-Frequenz-Beziehung und Aktivität der Ca2+-ATPase des
sarkoplasmatischen Retikulums im menschlichen Myokard.
Z Kardiol, 1998; 87 (Suppl 1): 51

Marra DE, Laufs U, Liao JK
Differential effects of nitric oxide and antioxidants on cyclin
dependent kinase inhibitors in vascular smooth muscle cells.
J Invest Med, 1998; 46(3): 202A

Michaelsen F, Müller C, Nickenig G
Charakterisierung der AT1 Rezeptor mRNA Bindungsproteine.
Z Kardiol, 1998; 87,1: 103

Müller-Ehmsen J, Diedrichs H, Thompson CB, Wang J, Frank K,
McDonough AA, Schwinger RHG
Decreased protein level and activity of the Na+/K+-ATPase but
unchanged abundance and activity of the Na+/Ca 2+-exchanger in
the failing human myocardium.
Eur Heart J, 1998; (Suppl) 19: P2232

Müller-Ehmsen J, Schwinger RHG, Wang JN, Frank K, McDonough
AA
Increased sensitivity towards Na+ -channel modulator BDF 9198 in
failing human heart with reduced sodium pump levels.
FASEB J, 1998; 12: A 409

Nickenig G, Bäumer AT, Grohe C, Vetter H, Böhm M
AT1 receptor regulation by estrogen in vitro and in vivo.
Kidney Blood Press Res, 1998; 21 (Suppl): 372

Nickenig G, Bäumer AT, Jockenhövel F, Müller-Wieland D, Krone
W, Böhm M
Heraufregulation des AT1 Rezeptors in hypercholesterinämischen
Patienten.
Z Kardiol, 1998; 87 (Suppl 1): 103

Nickenig G, Bäumer AT, Jockenhövel F, Müller-Wieland D, Krone
W, Böhm M
Hypercholesterolaemia induces AT1 receptor up-regulation in
humans.
Eur Heart J, 1998; 19: P3489

Nickenig G, Röling J, Strehlow K, Schnabel P, Böhm M
Insulin induziert eine posttranskriptioonell-mediierte
AT1-Rezeptor-Überexpression.
Z Kardiol, 1998; 87 (Suppl 1): 7

Nickenig G, Röling J, Strehlow K, Schnabel P, Böhm M
Insulin induces up-regulation of vascular AT1 receptor gene
expression by posttranscriptional mechanisms.
Eur Heart J, 1998; 19: 376

Nickenig G, Strehlow K, Roeling J, Böhm M
Sodium chloride causes AT1 receptor overexpression in vitro and in
vivo.
Circulation, 1998 98 (Suppl I): 420

Nickenig G, Strehlow K, Roeling J, Zolk O, Böhm M
Salt induces vascular AT1 receptor overexpression in vitro and in
vivo.
Eur Heart J, 1998; 19: 3411

Nickenig G, Wolf M, Böhm M
Enhanced expression and antoimmunity of recombinant binding
protein-jk in human dilated cardiomyopathy.
Circulation, 1998; 98 (Suppl I): 406

Nickenig G, Wolff M, Stäblein A, Böhm M
Enhanced expression and autoimmunity of recombinant
bindung-protein-j in human dilated cardiomyopathy.
Eur Heart J, 1998; 19: 518

Owen VJ, Burton PBJ, Zolk O, Böhm M, Michel MC, Barton P,
Yacoub MH, Harding SE
Gi activity and ß-adrenoceptor density in donor hearts not suitable
for transplantation "due to brain-death induced" myocardial failure.
Eur Heart J, 1998; 19: P1063

Quattek JM, Zolk O, Schrader T, Sitzler G, Böhm M
Expression of the endothelin system in failing human left ventricular
myocardium.
Naunyn-Schmiedeberg's Arch Pharmacol, 1998; 357 (Suppl 4): R
110

Priebe L, Beuckelmann DJ
Frequenzabhängigkeit der intrazellulären Calcium-Transienten und
des L-Typ Calciumstroms in ventrikulären Herzmuskelzellen.
Z Kardiol, 1998; (Suppl. I) 87: 52

Priebe L, Beuckelmann DJ
Frequency dependence of the intracellular calcium transient and the
L-type calcium current in ventricular myocytes of failing human
hearts.
Eur Heart J 1998; 19: 4o6

Priebe L, Beuckelmann DJ
Cell swelling results in action potential shortening by inducing IKAT in
guinea pig ventricular myocytes.
Eur Heart J, 1998; (Suppl) 19: 43

Priebe L, Beuckelmann DJ
A simulation study of cellular electric properties in heart failure.
Eur Heart J, 1998; 19: 78

Priebe L, Beuckelmann DJ
Cell swelling causes action potential shortening by activating the
ATP-sensitive potassium current in guinea pig ventricular myocytes.
Circulation, 1998; (Suppl) 98: I-695

Serruys PW, van Hout BA, Koens B, Marshall P, Rutsch W, Te Riele
J, Crean PA, Höpp HW, Melkert R, Norel R

Q: Who "cost-benefits" the most from stenting? A: The unstable with
a LAD lesion in a vessel size.
Eur Heart J, 1998; 19 (Suppl)

Schnabel P, Mies F, Maack C, Zolk O, Rosenkranz S, Böhm M
The effect of amiodarone on the ß-adrenoceptor-G-protein-adenylyl
cyclase system in human myocardium and in isolated rat
cardiomyocytes.
Eur Heart J, 1998; 19: P1065

Schnabel P, Mies F, Nohr T, Nickenig G, Böhm M
Insulin-like growth factor-I-induced hypertrophy in cultured rat
cardiomyocytes.
Eur Heart J, 1998; J 19: 940

Schnabel P, Nohr T, Mies F, Nickenig G, Böhm M
G protein-coupled signal transduction in norepinephrine- and
serum-induced cardiac hypertrophy.
Eur Heart J, 1998; 19: P1558

Schneider CA, Baer FM, Horst H, Erdmann E, Sechtem U
Significance of exercise - induced ST-segment elevation and T
wave pseudonormalization for improvement of function in patients
with Q-wave myocardial infarction.
Eur Heart J, 1998; (Suppl) 19: 1881

Schneider CA, Voth E, Gawlich S, Horst M, Schicha H, Erdmann E,
Sechtem U, Baer FM
Prognostic significance of rest-technetium-99 m sestamibi imaging
for the prediction of improvement of left ventricular dysfunction after
myocardial infarction: importance of infarct location adjusted
thresholds.
Eur Heart J, 1998; (Suppl) 19: P677

Schneider CA, Voth E, Crnac J, Moka D, Schicha H, Erdmann E,
Sechtem U
Improvement of myocardial blood flow to ischemic regions by ACE
inhibition with quinaprilate: a 150 water positron emission
tomography study with dobutamine stress.
Circulation, 1998; (Suppl) I-577

Schwinger RHG, Bölck B, Frank K, Brixius K, Münch G
Poly-unsaturated fatty acids excert a positive effect on the
force-frequency relation in human failing myocardium via activation
of SERCA 2.
Eur Heart J, 1998; (Suppl) 19: P2231

Schwinger RHG, Bölck B, Münch G
Reduced SERCA 2 activity due to decreased Ca-kinase dependent
phosphorylation in failing human myocardium.
Eur Heart J, 1998; (Suppl) 19: P2230

Schwinger RHG, Reuter H, Reicke S, Müller-Ehmsen J, Brixius K
Erhöhte Myosin-ATPase / Kraft-Relation am insuffizienten
menschlichen Myokard.
Z Kardiol, 1997; 87 (Suppl 1) 309

Schwinger RHG, Reuter H, Reicke S, Zobel C, Brixius K
Increased myosin ATPase/force ratio in human failing compared to
nonfailing myocardium.
Eur Heart J, 1998; (Suppl) 19: P2233

Schwinger RHG, Sawidou-Zaroti P, Brixius K
Decreased Ca2+-sensitivity of tension development and myosin
ATPase activity in left ventricular skinned fiber preparations of rats
harboring the murine Ren-2 gene.
Eur Heart J, 1998; (Suppl) 19: P1553

Schwinger RHG, Zobel C, Brixius K
Influence of the Na+-channel modulator BDF 9148 on Ca2+
-sensitivity and force of contraction on myocardium from transgene
rats with renin induced hyoertension (TG(mREN2)27).
Eur Heart J, 1998; (Suppl) 19: P1554

Stoll R, Franzen D, Karabacak D, Korsten J, Höpp HW
Endoluminale Thromben bei stabiler koronarer Herzkrankheit.
Z Kardiol, 1998; (Suppl) 87:V-18

Waagstein F, Wahlqvist I, Andersson B, Böhm M, Darius W, Delius
W, Dietz R, Goss F, Sigmund M, Strömblad SO, Trenkwalder P
Metoprolol prevents left ventricular dilatation and increases exercise
ejection fraction to the same extent in idiopathic dilated and
ischaemic cardiomyopathy.
Eur Heart J, 1998; 19: P1722

Waßmann S, Nickenig G, Böhm M
Atorvastatin down-regulates AT1 receptor gene expression.
Eur Heart J, 1998;19: 807

Waßmann S, Nickenig G, Böhm M
HMG-CoA reductase inhibitor atorvastatin downregulates
AT1-receptor gene expression and cell proliferation in vascular
smooth muscle cells.
Kidney Blood Press Res, 1998; 21 (Suppl): 392

Zobel C, Brixius K, Müller-Ehmsen J, Münch G, Bölck B, Hoischen S,
Schwinger RHG
Abhängigkeit der tetanischen Kontraktion vom Ca2+-Einstrom über
den L-Typ Ca2+-Kanal am menschlichen Myokard.
Z Kardiol, 1997; 87 (Suppl 1) 315

Zolk O, Kilter H, Mansier P, Swynghedauw B, Böhm M
Altered functional coupling of overexpressed myocardial
ß1-adreneceptors in transgenic mice.
Eur Heart J, 1998; 19: 2705

Zolk O, Quattek J, Sitzler G, Schrader T, Böhm M
Veränderungen des Expressionsmusters von Komponenten des
Endothelinsystems im menschlichen insuffizienten linksventrikulären
Myokard.
Z Kardiol, 1998; 87 (Suppl 1): 49

Zolk O, Quattek J, Schrader T, Sitzler G, Nickenig G, Schnabel P,
Böhm M
Alterations of the cardiac endothelin system in human end-stage
heart failure.
Circulation, 1998; 98 (Suppl I): 551

Zolk O, Quattek J, Schrader T, Sitzler G, Nickenig G, Schnabel P,
Shimada K, Böhm M
Alterations of the cardiac endothelin system in human end-stage
heart failure.
Eur Heart J, 1998; 19: 1988

Zolk O, Schrader T, Sitzler G, Böhm M
The cardiac endothelin system in human end-stage heart failure.
Kidney Blood Press Res, 1998; 21 (Suppl): 396

Wissenschaftliche Preise

Erdmann E
Lingen Preis, 1998

Karasch T
Vascular diagnosis with ultrasound: clinical references with case
studies.
BMA Medical Book Competition Awards
First Prize

Laufs U
International Young Investigator Award of the American College of
Cardiology,
Erster Platz, 1998

Laufs U
Oskar-Lapp-Preis, Deutsche Gesellschaft für Kardiologie,
Erster Platz, 1998